Tirzepatide vs semaglutide, at wholesale

Tirzepatide and semaglutide are the two most-asked-for metabolic peptides on a wholesale list. This is how they compare as stock to carry, by what they are and what they cost per mg. It is a sourcing comparison, not a clinical one: everything here is supplied for research use only.

What each one is

Semaglutide is an acylated GLP-1 receptor analogue, a 31-residue peptide with a fatty-acid side chain.
Tirzepatide is an acylated GIP and GLP-1 receptor co-agonist, a larger 39-residue peptide. It acts at two receptors where semaglutide acts at one.

At wholesale

Semaglutide: 7 sizes, from £0.225 /mg, batch COA.
Tirzepatide: 12 sizes, from £0.215 /mg, batch COA. Tirzepatide is stocked in more sizes.

Both are held to the same release, not less than 98 percent by RP-HPLC with a certificate per batch, and both price per box, per vial and per mg on their pages. The larger vial is cheaper per mg on each.

Which to carry

Most resellers carry both: they are the headline metabolic lines and buyers ask for them by name. Stock a range of sizes of each so a customer can buy the vial that fits, and lead with the per-mg figure. See the whole metabolic range, retatrutide vs tirzepatide, or the GLP-1 wholesale guide.

Common questions

What is the difference between tirzepatide and semaglutide?

Chemically, semaglutide is a 31-residue acylated GLP-1 receptor analogue; tirzepatide is a larger 39-residue acylated GIP and GLP-1 receptor co-agonist. Both are supplied for research use only.

Which is cheaper per mg at wholesale?

Both are priced per mg on their pages, from £0.225 /mg (semaglutide) and £0.215 /mg (tirzepatide) on the keenest size. The larger vial is cheaper per mg on each.

Should a reseller stock both?

Usually yes. They are the most-requested metabolic lines; carrying a range of sizes of each lets a customer buy the vial that fits.