GHRP-6 research: what the studies have looked at

This page summarises the published research on GHRP-6, for reference. It states what each study investigated and in whom, not an effect to expect, and it is not medical advice. GHRP-6 is used in human endocrine research but is not an approved medicine; what we supply is a research chemical for laboratory use only.

What GHRP-6 is

GHRP-6 is a synthetic six-amino-acid growth-hormone secretagogue that acts on the ghrelin receptor (GHS-R1a) to release growth hormone from the pituitary. It has been used as an investigational and diagnostic tool in human endocrine research; it has not been approved as a medicine.

What the studies investigated

Popovic et al. (2000), The Lancet 356(9236):1137-1142. Human. Investigated a GHRH-plus-GHRP-6 test against the insulin-tolerance test for diagnosing growth-hormone deficiency Source.

Pandya et al. (1998), Journal of Clinical Endocrinology and Metabolism 83(4):1186-1189. Human. Reported that a GHRH antagonist eliminated the GHRP-6 growth-hormone response Source.

Frieboes et al. (1995), Neuroendocrinology 61(5):584-589. Human. Investigated the effect on sleep EEG and nocturnal growth-hormone secretion Source.

Mechanism, as described in the literature

The literature describes GHRP-6 as a ghrelin-receptor (GHS-R1a) agonist that drives a pulse of growth-hormone release, an effect that depends in part on the body’s own growth-hormone-releasing hormone. It has been used in humans mainly as a diagnostic stimulus and as a probe of the growth-hormone axis, not as a treatment.

The material we supply

We supply GHRP-6 as a research chemical, released against a written specification with a batch certificate of analysis. It is not an approved medicine and is not for human or animal use. For the vial sizes, the price per mg and how to order, see the GHRP-6 compound page; the COA lookup pulls the certificate for any batch. The references above link to each study’s record; this summary is for research and educational reference only.